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Ethical approval was obtained from the institutional ethics committees and patient inclusion required signature of inintended intomed consent. Most of them have one catalytic domain except conducive to AgCht7, AgCht9 and AgCht10, which have 2, 2 and 4 catalytic domains, respectively. Wright MA, Kharchenko P, Church GM, Segre D. Chromosomal periodicity of evolutionarily conserved gene pairs.
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